Cog

Theme Cog

Meet the COG ’ s

Kinematics combined with detailed element abundances provide a method of analysis of stellar populations that uses as much available information as possible, in contrast to other methods. Here we employ this technique on local A-type horizontal branch stars in an ongoing programme to search for ω Centauri debris among these objects. This led us to discover another group of stars with very simil...

Histone modification: cause or cog?

Histone modifications are key components of chromatin packaging but whether they constitute a 'code' has been contested. We believe that the central issue is causality: are histone modifications responsible for differences between chromatin states, or are differences in modifications mostly consequences of dynamic processes, such as transcription and nucleosome remodeling? We find that inferenc...

Cog as a thought experiment

In her presentation at the Monte Verità workshop, Maja Mataric showed us a videotape of her robots cruising together through the lab, and remarked, aptly: "They're flocking, but that's not what they think they're doing." This is a vivid instance of a phenomenon that lies at the heart of all the research I learned about at Monte Verità: the execution of surprisingly successful "cognitive" behavi...

COG Complex Complexities: Detailed Characterization of a Complete Set of HEK293T Cells Lacking Individual COG Subunits

The Conserved Oligomeric Golgi complex is an evolutionarily conserved multisubunit tethering complex (MTC) that is crucial for intracellular membrane trafficking and Golgi homeostasis. The COG complex interacts with core vesicle docking and fusion machinery at the Golgi; however, its exact mechanism of action is still an enigma. Previous studies of COG complex were limited to the use of CDGII (...